A substance in red wine that’s been theorized to have anti-aging effects appears to be safe for individuals with Alzheimer’s disease, and may lead to a new alternative way to treat the disease, early investigative studies suggest.
Taken from the research, about 120 people with Alzheimer’s disease took either a form of medicine made from the compound, called resveratrol, or a placebo, every day for a year. The amount of resveratrol was high about the equivalent of the amount discovered in 1,000 bottles of red wine, the researchers stated.
Resveratrol seemed to have an effect on levels of a protein called amyloid-beta40, or Abeta40. Most times as Alzheimer’s disease get increasingly worse, the levels of Abeta40 lower in humans cerebrospinal fluid (CSF), which surrounds the brain and spinal cord. Investigators have an idea that this decline happens because Abeta40 builds up in the brain instead of the CSF, leading to symptoms of Alzheimer’s disease.
Individuals who took part of the research and took a placebo had a decrease in Abeta40 in their spinal fluid in the mid of the study period, however those who took resveratrol had little or no alteration in their levels of Abet40, the researchers stated.
This research suggests that the resveratrol treatment may have led to less Abeta40 deposits in the brain, however the people conducting the research will need to confirm this in future research that look at levels of the amyloid protein in the brain. So as of now, doctors don’t know if resveratrol impacts the progression of the disease.